Stem Cell

Cardiac stem cells from young hearts can make older hearts young, study says

A new study from the Cedars-Sinai Heart Institute, Los Angeles, published by the European Heart Journal, forecasts the use of infusions of cardiac stem cells obtained from young hearts in reversing the process of aging in the human heart.

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According to this animal study, tiny vesicles that have the capability to ‘reverse the clock’ for age-related heart conditions are secreted by the cardiosphere-derived cells (CDCs) – a particular stem cell type – making older hearts behave younger.

Eduardo Marbán, MD, PhD, director of the Cedars-Sinai Heart Institute and the primary investigator of the study said, according to their previous lab studies as well as human clinical trials, cardiac stem cell infusions were seen to be effective in treating heart failure; the present study promises the use of these specialized stem cells in reversing age-related heart problems.

In the trial, CDCs obtained from newborn laboratory rats were injected into the hearts of the rats that were on an average of 22 months old and considered aged. A placebo treatment of saline injections was received by a set of laboratory rats from the same group. Then, both these groups were compared with a set of young rats that were…